| 2021-04-17 16:30:0017/04/21 |   Atletico Tirrena Cv — Littoriana Futsal C.5 | 3 - 3 | Campetti di San Liborio |
| 2021-04-17 17:00:0017/04/21 |   Real Praeneste — Virtus Fondi Calcio a 5 | 9 - 5 | Petroselli Luigi |
| 2021-04-17 18:30:0017/04/21 |   La Coccinella — Roma Calcio Femminile | 6 - 2 | Coccinella C.S. |
| 2021-04-17 20:00:0017/04/21 |   Trastevere Calcio — Futsal Pontinia | 0 - 0 | Trastevere Stadium |
| 2021-04-24 15:00:0024/04/21 | Virtus Fondi Calcio a 5 — Atletico Tirrena Cv | 15:00:0015:00 | Palazzetto dello Sport |
| 2021-04-24 16:00:0024/04/21 | Futsal Pontinia — La Coccinella | 16:00:0016:00 | PalaPontinia |
| 2021-04-24 18:00:0024/04/21 | Roma Calcio Femminile — Real Praeneste | 18:00:0018:00 | Palatorrino |
| 2021-04-24 21:00:0024/04/21 | Littoriana Futsal C.5 — Trastevere Calcio | 21:00:0021:00 | - |
| 2021-05-01 16:30:0001/05/21 | Atletico Tirrena Cv — Roma Calcio Femminile | 16:30:0016:30 | Campetti di San Liborio |
| 2021-05-01 17:00:0001/05/21 | Real Praeneste — La Coccinella | 17:00:0017:00 | Petroselli Luigi |
| 2021-05-01 20:00:0001/05/21 | Trastevere Calcio — Virtus Fondi Calcio a 5 | 20:00:0020:00 | Trastevere Stadium |
| 2021-05-01 21:00:0001/05/21 | Littoriana Futsal C.5 — Futsal Pontinia | 21:00:0021:00 | - |
| 2021-05-08 15:00:0008/05/21 | Virtus Fondi Calcio a 5 — Littoriana Futsal C.5 | 15:00:0015:00 | Palazzetto dello Sport |
| 2021-05-08 16:00:0008/05/21 | Futsal Pontinia — Real Praeneste | 16:00:0016:00 | PalaPontinia |
| 2021-05-08 18:00:0008/05/21 | Roma Calcio Femminile — Trastevere Calcio | 18:00:0018:00 | Palatorrino |
| 2021-05-08 18:30:0008/05/21 | La Coccinella — Atletico Tirrena Cv | 18:30:0018:30 | Coccinella C.S. |
| 2021-05-15 15:00:0015/05/21 | Virtus Fondi Calcio a 5 — Futsal Pontinia | 15:00:0015:00 | Palazzetto dello Sport |
| 2021-05-15 16:30:0015/05/21 | Atletico Tirrena Cv — Real Praeneste | 16:30:0016:30 | Campetti di San Liborio |
| 2021-05-15 20:00:0015/05/21 | Trastevere Calcio — La Coccinella | 20:00:0020:00 | Trastevere Stadium |
| 2021-05-15 21:00:0015/05/21 | Littoriana Futsal C.5 — Roma Calcio Femminile | 21:00:0021:00 | - |
| 2021-05-22 16:30:0022/05/21 | Atletico Tirrena Cv — Futsal Pontinia | 16:30:0016:30 | Campetti di San Liborio |
| 2021-05-22 17:00:0022/05/21 | Real Praeneste — Trastevere Calcio | 17:00:0017:00 | Petroselli Luigi |
| 2021-05-22 18:00:0022/05/21 | Roma Calcio Femminile — Virtus Fondi Calcio a 5 | 18:00:0018:00 | Palatorrino |
| 2021-05-22 18:30:0022/05/21 | La Coccinella — Littoriana Futsal C.5 | 18:30:0018:30 | Coccinella C.S. |
| 2021-05-29 15:00:0029/05/21 | Virtus Fondi Calcio a 5 — La Coccinella | 15:00:0015:00 | Palazzetto dello Sport |
| 2021-05-29 16:00:0029/05/21 | Futsal Pontinia — Roma Calcio Femminile | 16:00:0016:00 | PalaPontinia |
| 2021-05-29 20:00:0029/05/21 | Trastevere Calcio — Atletico Tirrena Cv | 20:00:0020:00 | Trastevere Stadium |
| 2021-05-29 21:00:0029/05/21 | Littoriana Futsal C.5 — Real Praeneste | 21:00:0021:00 | - |
Real Praeneste
La Coccinella
Atletico Tirrena CV
Littoriana Futsal C.5
Futsal Pontinia
Trastevere Calcio
Virtus Fondi Calcio A 5
Roma Calcio Femminile
