| 2021-10-09 15:00:0009/10/21 |   U.S. Cures C.a 5 — Futsal Tor Sapienza | 9 - 2 | Palazzetto Palasabina |
| 2021-10-09 15:00:0009/10/21 |   Sportingclub Santos Mmxix — Atletico Pavona | 2 - 8 | Valle Aurelia |
| 2021-10-09 15:00:0009/10/21 |   Real Mattei — Circolo Master 97 | 2 - 0 | Empire Roma |
| 2021-10-09 15:00:0009/10/21 |   Bfsport — Ls10 | 4 - 1 | Palasantarufina |
| 2021-10-09 18:30:0009/10/21 |  Virtus Ostia C.5 — Conauto Lidense C.a5 | 1 - 3 | Lodovichetti A.C5 |
| 2021-10-09 18:30:0009/10/21 |   Circolo Canottieri Lazio — Futsal Settecamini | 12 - 3 | San Gaetano C5 |
| 2021-10-09 20:39:4309/10/21 |  Riposa - Futsal Tor Sapienza | 20:39:4320:39 | - |
| 2021-10-16 15:00:0016/10/21 | Ls10 — Real Mattei | 3 - 5 | Virtus Antica Aurelia |
| 2021-10-16 15:00:0016/10/21 | Futsal Tor Sapienza — Virtus Ostia C.5 | 2 - 7 | Supreme Sport Village |
| 2021-10-16 15:00:0016/10/21 | Conauto Lidense C.a5 — Circolo Canottieri Lazio | 2 - 1 | Lodovichetti A.C5 |
| 2021-10-16 15:30:0016/10/21 | Circolo Master 97 — Sportingclub Santos Mmxix | 3 - 3 | Master |
| 2021-10-16 16:00:0016/10/21 |  Futsal Settecamini — Epiro C.a 5 | 1 - 3 | G-Sportvillage |
| 2021-10-16 16:15:0016/10/21 | Atletico Pavona — U.S. Cures C.a 5 | 3 - 3 | Ok Club |
| 2021-10-16 20:29:1316/10/21 | Riposa - BF Sport | 20:29:1320:29 | - |
| 2021-10-23 15:00:0023/10/21 | U.S. Cures C.a 5 — Circolo Master 97 | 10 - 4 | Palazzetto Palasabina |
| 2021-10-23 15:00:0023/10/21 | Sportingclub Santos Mmxix — Ls10 | 2 - 1 | Valle Aurelia |
| 2021-10-23 15:00:0023/10/21 | Real Mattei — Bfsport | 3 - 2 | Empire Roma |
| 2021-10-23 15:30:0023/10/21 | Riposa — Futsal Settecamini | 15:30:0015:30 | - |
| 2021-10-23 18:00:0023/10/21 | Epiro C.a 5 — Conauto Lidense C.a5 | 1 - 0 | Tobia Mario |
| 2021-10-23 18:30:0023/10/21 | Virtus Ostia C.5 — Atletico Pavona | 4 - 5 | Lodovichetti A.C5 |
| 2021-10-23 18:30:0023/10/21 | Circolo Canottieri Lazio — Futsal Tor Sapienza | 5 - 4 | San Gaetano C5 |
| 2021-10-30 15:00:0030/10/21 | Ls10 — U.S. Cures C.a 5 | 1 - 6 | Virtus Antica Aurelia |
| 2021-10-30 15:00:0030/10/21 | Futsal Tor Sapienza — Epiro C.a 5 | 5 - 2 | Supreme Sport Village |
| 2021-10-30 15:00:0030/10/21 | Conauto Lidense C.a5 — Futsal Settecamini | 4 - 0 | Lodovichetti A.C5 |
| 2021-10-30 15:00:0030/10/21 | Bfsport — Sportingclub Santos Mmxix | 2 - 2 | Palasantarufina |
| 2021-10-30 15:30:0030/10/21 | Riposa — Real Mattei | 15:30:0015:30 | |
| 2021-10-30 15:30:0030/10/21 | Circolo Master 97 — Virtus Ostia C.5 | 6 - 8 | Master |
| 2021-10-30 16:15:0030/10/21 | Atletico Pavona — Circolo Canottieri Lazio | 8 - 4 | Ok Club |
| 2021-11-06 15:00:0006/11/21 | U.S. Cures C.a 5 — Bfsport | 1 - 0 | Palazzetto Palasabina |
| 2021-11-06 15:00:0006/11/21 | Sportingclub Santos Mmxix — Real Mattei | 1 - 6 | Valle Aurelia |
| 2021-11-06 15:30:3906/11/21 | Ripos. - Conauto Lidense C. a5 | 15:30:3915:30 | |
| 2021-11-06 16:00:0006/11/21 | Futsal Settecamini — Futsal Tor Sapienza | 5 - 9 | G-Sportvillage |
| 2021-11-06 18:00:0006/11/21 | Epiro C.a 5 — Atletico Pavona | 1 - 1 | Tobia Mario |
| 2021-11-06 18:30:0006/11/21 | Virtus Ostia C.5 — Ls10 | 10 - 2 | Lodovichetti A.C5 |
| 2021-11-06 18:30:0006/11/21 | Circolo Canottieri Lazio — Circolo Master 97 | 5 - 1 | San Gaetano C5 |
| 2021-11-13 15:00:0013/11/21 | Real Mattei — U.S. Cures C.a 5 | 2 - 2 | Empire Roma |
| 2021-11-13 15:00:0013/11/21 | Ls10 — Circolo Canottieri Lazio | 3 - 5 | Virtus Antica Aurelia |
| 2021-11-13 15:00:0013/11/21 | Futsal Tor Sapienza — Conauto Lidense C.a5 | 3 - 1 | Supreme Sport Village |
| 2021-11-13 15:00:0013/11/21 | Bfsport — Virtus Ostia C.5 | 3 - 2 | Palasantarufina |
| 2021-11-13 15:30:0013/11/21 | Riposa — Sportingclub Santos MMXIX | 15:30:0015:30 | - |
| 2021-11-13 15:30:0013/11/21 | Circolo Master 97 — Epiro C.a 5 | 2 - 8 | Master |
| 2021-11-13 16:15:0013/11/21 | Atletico Pavona — Futsal Settecamini | 7 - 2 | Ok Club |
| 2021-11-20 15:00:0020/11/21 | U.S. Cures C.a 5 — Sportingclub Santos Mmxix | 3 - 2 | Palazzetto Palasabina |
| 2021-11-20 15:00:0020/11/21 | Conauto Lidense C.a5 — Atletico Pavona | 2 - 3 | Lodovichetti A.C5 |
| 2021-11-20 15:30:0020/11/21 | Riposa — Futsal Tor Sapienza | 15:30:0015:30 | - |
| 2021-11-20 16:00:0020/11/21 | Futsal Settecamini — Circolo Master 97 | 4 - 5 | G-Sportvillage |
| 2021-11-20 18:00:0020/11/21 | Epiro C.a 5 — Ls10 | 4 - 2 | Tobia Mario |
| 2021-11-20 18:30:0020/11/21 | Virtus Ostia C.5 — Real Mattei | 2 - 3 | Lodovichetti A.C5 |
| 2021-11-20 18:30:0020/11/21 | Circolo Canottieri Lazio — Bfsport | 4 - 1 | San Gaetano C5 |
| 2021-11-27 15:00:0027/11/21 | Sportingclub Santos Mmxix — Virtus Ostia C.5 | 1 - 5 | Valle Aurelia |
| 2021-11-27 15:00:0027/11/21 | Real Mattei — Circolo Canottieri Lazio | 5 - 2 | Empire Roma |
| 2021-11-27 15:00:0027/11/21 | Ls10 — Futsal Settecamini | 6 - 8 | Virtus Antica Aurelia |
| 2021-11-27 15:00:0027/11/21 | Bfsport — Epiro C.a 5 | 3 - 2 | Palasantarufina |
| 2021-11-27 15:30:0027/11/21 | Riposa — U.S.Cures Calcio a 5 | 15:30:0015:30 | - |
| 2021-11-27 15:30:0027/11/21 | Circolo Master 97 — Conauto Lidense C.a5 | 5 - 4 | Master |
| 2021-11-27 16:15:0027/11/21 | Atletico Pavona — Futsal Tor Sapienza | 9 - 2 | Ok Club |
| 2021-12-04 15:00:0004/12/21 | Futsal Tor Sapienza — Circolo Master 97 | 8 - 6 | Supreme Sport Village |
| 2021-12-04 15:00:0004/12/21 | Conauto Lidense C.a5 — Ls10 | 5 - 2 | Lodovichetti A.C5 |
| 2021-12-04 15:30:0004/12/21 | Riposa — Atletico Pavona | 15:30:0015:30 | - |
| 2021-12-04 16:00:0004/12/21 | Futsal Settecamini — Bfsport | 3 - 5 | G-Sportvillage |
| 2021-12-04 18:00:0004/12/21 | Epiro C.a 5 — Real Mattei | 4 - 2 | Tobia Mario |
| 2021-12-04 18:30:0004/12/21 | Virtus Ostia C.5 — U.S. Cures C.a 5 | 1 - 1 | Lodovichetti A.C5 |
| 2021-12-04 18:30:0004/12/21 | Circolo Canottieri Lazio — Sportingclub Santos Mmxix | 7 - 4 | San Gaetano C5 |
| 2021-12-11 15:00:0011/12/21 | U.S. Cures C.a 5 — Circolo Canottieri Lazio | 2 - 1 | Palazzetto Palasabina |
| 2021-12-11 15:00:0011/12/21 | Sportingclub Santos Mmxix — Epiro C.a 5 | Rinv | Valle Aurelia |
| 2021-12-11 15:00:0011/12/21 | Real Mattei — Futsal Settecamini | 4 - 1 | Empire Roma |
| 2021-12-11 15:00:0011/12/21 | Ls10 — Futsal Tor Sapienza | 3 - 8 | Virtus Antica Aurelia |
| 2021-12-11 15:00:0011/12/21 | Bfsport — Conauto Lidense C.a5 | 4 - 4 | Palasantarufina |
| 2021-12-11 15:30:0011/12/21 | Riposa — Virtus Ostia C5 | 15:30:0015:30 | - |
| 2021-12-11 15:30:0011/12/21 | Circolo Master 97 — Atletico Pavona | 5 - 4 | Master |
| 2021-12-18 15:00:0018/12/21 | Futsal Tor Sapienza — Bfsport | 11 - 3 | Supreme Sport Village |
| 2021-12-18 15:00:0018/12/21 | Conauto Lidense C.a5 — Real Mattei | 4 - 0 | Lodovichetti A.C5 |
| 2021-12-18 15:30:0018/12/21 | Riposa — Circolo Master 97 | 15:30:0015:30 | - |
| 2021-12-18 16:00:0018/12/21 | Futsal Settecamini — Sportingclub Santos Mmxix | 1 - 2 | G-Sportvillage |
| 2021-12-18 16:15:0018/12/21 | Atletico Pavona — Ls10 | 4 - 1 | Ok Club |
| 2021-12-18 18:00:0018/12/21 | Epiro C.a 5 — U.S. Cures C.a 5 | 2 - 2 | Tobia Mario |
| 2021-12-18 18:30:0018/12/21 | Circolo Canottieri Lazio — Virtus Ostia C.5 | 2 - 6 | San Gaetano C5 |
| 2022-01-08 15:00:0008/01/22 | U.S. Cures C.a 5 — Futsal Settecamini | 3 - 2 | Palazzetto Palasabina |
| 2022-01-08 15:00:0008/01/22 | Sportingclub Santos Mmxix — Conauto Lidense C.a5 | 0 - 2 | Valle Aurelia |
| 2022-01-08 15:00:0008/01/22 | Real Mattei — Futsal Tor Sapienza | 3 - 4 | Empire Roma |
| 2022-01-08 15:00:0008/01/22 | Ls10 — Circolo Master 97 | 3 - 10 | Virtus Antica Aurelia |
| 2022-01-08 15:00:0008/01/22 | Bfsport — Atletico Pavona | 2 - 1 | Palasantarufina |
| 2022-01-08 15:30:0008/01/22 | Riposa — Circolo Canottieri Lazio | 15:30:0015:30 | - |
| 2022-01-08 18:30:0008/01/22 | Virtus Ostia C.5 — Epiro C.a 5 | 18:30:0018:30 | Lodovichetti A.C5 |
| 2022-02-05 15:00:0005/02/22 | Riposa — LS10 | 15:00:0015:00 | - |
| 2022-02-05 15:00:0005/02/22 | Futsal Tor Sapienza — Sportingclub Santos Mmxix | 3 - 4 | Supreme Sport Village |
| 2022-02-05 15:00:0005/02/22 | Conauto Lidense C.a5 — U.S. Cures C.a 5 | 4 - 1 | Lodovichetti A.C5 |
| 2022-02-05 15:30:0005/02/22 | Circolo Master 97 — Bfsport | 2 - 2 | Master |
| 2022-02-05 16:00:0005/02/22 | Futsal Settecamini — Virtus Ostia C.5 | 2 - 4 | G-Sportvillage |
| 2022-02-05 16:15:0005/02/22 | Atletico Pavona — Real Mattei | 4 - 4 | Ok Club |
| 2022-02-05 18:00:0005/02/22 | Epiro C.a 5 — Circolo Canottieri Lazio | 2 - 1 | Tobia Mario |
| 2022-02-12 15:00:0012/02/22 | Ls10 — Bfsport | 4 - 5 | Virtus Antica Aurelia |
| 2022-02-12 15:00:0012/02/22 | Futsal Tor Sapienza — U.S. Cures C.a 5 | 3 - 6 | Supreme Sport Village |
| 2022-02-12 15:00:0012/02/22 | Conauto Lidense C.a5 — Virtus Ostia C.5 | 3 - 1 | Lodovichetti A.C5 |
| 2022-02-12 15:30:0012/02/22 | Epiro Calcio a 5 — Riposa | 15:30:0015:30 | - |
| 2022-02-12 15:30:0012/02/22 | Circolo Master 97 — Real Mattei | 5 - 2 | Master |
| 2022-02-12 16:00:0012/02/22 | Futsal Settecamini — Circolo Canottieri Lazio | 2 - 10 | G-Sportvillage |
| 2022-02-12 16:15:0012/02/22 | Atletico Pavona — Sportingclub Santos Mmxix | 4 - 4 | Ok Club |
| 2022-02-19 15:00:0019/02/22 | U.S. Cures C.a 5 — Atletico Pavona | 5 - 3 | Palazzetto Palasabina |
| 2022-02-19 15:00:0019/02/22 | Sportingclub Santos Mmxix — Circolo Master 97 | 1 - 9 | Valle Aurelia |
| 2022-02-19 15:00:0019/02/22 | Real Mattei — Ls10 | 4 - 1 | Empire Roma |
| 2022-02-19 15:30:0019/02/22 | BFSport — Riposa | 15:30:0015:30 | - |
| 2022-02-19 18:00:0019/02/22 | Epiro C.a 5 — Futsal Settecamini | 5 - 2 | Tobia Mario |
| 2022-02-19 18:30:0019/02/22 | Virtus Ostia C.5 — Futsal Tor Sapienza | 6 - 5 | Lodovichetti A.C5 |
| 2022-02-19 18:30:0019/02/22 | Circolo Canottieri Lazio — Conauto Lidense C.a5 | 4 - 6 | San Gaetano C5 |
| 2022-02-26 15:00:0026/02/22 | Ls10 — Sportingclub Santos Mmxix | 1 - 5 | Virtus Antica Aurelia |
| 2022-02-26 15:00:0026/02/22 | Futsal Tor Sapienza — Circolo Canottieri Lazio | 5 - 4 | Supreme Sport Village |
| 2022-02-26 15:00:0026/02/22 | Conauto Lidense C.a5 — Epiro C.a 5 | 1 - 1 | Lodovichetti A.C5 |
| 2022-02-26 15:00:0026/02/22 | Bfsport — Real Mattei | 3 - 2 | Palasantarufina |
| 2022-02-26 15:30:0026/02/22 | Futsal Settecamini — Riposa | 15:30:0015:30 | - |
| 2022-02-26 15:30:0026/02/22 | Circolo Master 97 — U.S. Cures C.a 5 | 1 - 1 | Master |
| 2022-02-26 16:15:0026/02/22 | Atletico Pavona — Virtus Ostia C.5 | 2 - 4 | Ok Club |
| 2022-03-05 15:00:0005/03/22 | U.S. Cures C.a 5 — Ls10 | 8 - 2 | Palazzetto Palasabina |
| 2022-03-05 15:00:0005/03/22 | Sportingclub Santos Mmxix — Bfsport | 11 - 1 | Valle Aurelia |
| 2022-03-05 15:30:0005/03/22 | Real Mattei — Riposa | 15:30:0015:30 | - |
| 2022-03-05 16:00:0005/03/22 | Futsal Settecamini — Conauto Lidense C.a5 | 1 - 7 | G-Sportvillage |
| 2022-03-05 18:00:0005/03/22 | Epiro C.a 5 — Futsal Tor Sapienza | 2 - 1 | Tobia Mario |
| 2022-03-05 18:30:0005/03/22 | Virtus Ostia C.5 — Circolo Master 97 | 18:30:0018:30 | Lodovichetti A.C5 |
| 2022-03-05 18:30:0005/03/22 | Circolo Canottieri Lazio — Atletico Pavona | 5 - 5 | San Gaetano C5 |
| 2022-03-12 15:00:0012/03/22 | Real Mattei — Sportingclub Santos Mmxix | 3 - 2 | Empire Roma |
| 2022-03-12 15:00:0012/03/22 | Ls10 — Virtus Ostia C.5 | 3 - 5 | Virtus Antica Aurelia |
| 2022-03-12 15:00:0012/03/22 | Futsal Tor Sapienza — Futsal Settecamini | 8 - 4 | Supreme Sport Village |
| 2022-03-12 15:00:0012/03/22 | Bfsport — U.S. Cures C.a 5 | 3 - 5 | Palasantarufina |
| 2022-03-12 15:30:0012/03/22 | Conauto Lidense C. a5 — Riposa | 15:30:0015:30 | - |
| 2022-03-12 15:30:0012/03/22 | Circolo Master 97 — Circolo Canottieri Lazio | 1 - 6 | Master |
| 2022-03-12 16:15:0012/03/22 | Atletico Pavona — Epiro C.a 5 | 3 - 1 | Ok Club |
| 2022-03-19 15:00:0019/03/22 | U.S. Cures C.a 5 — Real Mattei | 7 - 2 | Palazzetto Palasabina |
| 2022-03-19 15:00:0019/03/22 | Conauto Lidense C.a5 — Futsal Tor Sapienza | 4 - 4 | Lodovichetti A.C5 |
| 2022-03-19 15:30:0019/03/22 | Sportingclub Santos MMXIX — Riposa | 15:30:0015:30 | - |
| 2022-03-19 16:00:0019/03/22 | Futsal Settecamini — Atletico Pavona | 6 - 9 | G-Sportvillage |
| 2022-03-19 18:00:0019/03/22 | Epiro C.a 5 — Circolo Master 97 | 18:00:0018:00 | Tobia Mario |
| 2022-03-19 18:30:0019/03/22 | Virtus Ostia C.5 — Bfsport | 11 - 3 | Lodovichetti A.C5 |
| 2022-03-19 18:30:0019/03/22 | Circolo Canottieri Lazio — Ls10 | 6 - 2 | San Gaetano C5 |
| 2022-03-26 15:00:0026/03/22 | Sportingclub Santos Mmxix — U.S. Cures C.a 5 | 3 - 3 | Valle Aurelia |
| 2022-03-26 15:00:0026/03/22 | Real Mattei — Virtus Ostia C.5 | 1 - 2 | Empire Roma |
| 2022-03-26 15:00:0026/03/22 | Ls10 — Epiro C.a 5 | 3 - 7 | Virtus Antica Aurelia |
| 2022-03-26 15:00:0026/03/22 | Bfsport — Circolo Canottieri Lazio | 5 - 3 | Palasantarufina |
| 2022-03-26 15:30:0026/03/22 | Futsal Tor Sapienza — Riposa | 15:30:0015:30 | - |
| 2022-03-26 15:30:0026/03/22 | Circolo Master 97 — Futsal Settecamini | 5 - 4 | Master |
| 2022-03-26 16:15:0026/03/22 | Atletico Pavona — Conauto Lidense C.a5 | 4 - 5 | Ok Club |
| 2022-04-02 15:00:0002/04/22 | Futsal Tor Sapienza — Atletico Pavona | 4 - 9 | Supreme Sport Village |
| 2022-04-02 15:00:0002/04/22 | Conauto Lidense C.a5 — Circolo Master 97 | 7 - 0 | Lodovichetti A.C5 |
| 2022-04-02 15:30:0002/04/22 | U.S.Cures Calcio a 5 — Riposa | 15:30:0015:30 | - |
| 2022-04-02 16:00:0002/04/22 | Futsal Settecamini — Ls10 | 0 - 0 | G-Sportvillage |
| 2022-04-02 18:00:0002/04/22 | Epiro C.a 5 — Bfsport | 4 - 0 | Tobia Mario |
| 2022-04-02 18:30:0002/04/22 | Virtus Ostia C.5 — Sportingclub Santos Mmxix | 6 - 7 | Lodovichetti A.C5 |
| 2022-04-02 18:30:0002/04/22 | Circolo Canottieri Lazio — Real Mattei | 18:30:0018:30 | San Gaetano C5 |
| 2022-04-09 15:00:0009/04/22 | U.S. Cures C.a 5 — Virtus Ostia C.5 | 3 - 2 | Palazzetto Palasabina |
| 2022-04-09 15:00:0009/04/22 | Sportingclub Santos Mmxix — Circolo Canottieri Lazio | 4 - 3 | Valle Aurelia |
| 2022-04-09 15:00:0009/04/22 | Real Mattei — Epiro C.a 5 | 1 - 2 | Empire Roma |
| 2022-04-09 15:00:0009/04/22 | Ls10 — Conauto Lidense C.a5 | 4 - 9 | Virtus Antica Aurelia |
| 2022-04-09 15:00:0009/04/22 | Bfsport — Futsal Settecamini | 7 - 0 | Palasantarufina |
| 2022-04-09 15:30:0009/04/22 | Atletico Pavona — Riposa | 15:30:0015:30 | - |
| 2022-04-09 15:30:0009/04/22 | Circolo Master 97 — Futsal Tor Sapienza | 1 - 3 | Master |
| 2022-04-23 15:00:0023/04/22 | Futsal Tor Sapienza — Ls10 | 5 - 5 | Supreme Sport Village |
| 2022-04-23 15:00:0023/04/22 | Conauto Lidense C.a5 — Bfsport | 9 - 2 | Lodovichetti A.C5 |
| 2022-04-23 15:30:0023/04/22 | Virtus Ostia C5 — Riposa | 15:30:0015:30 | - |
| 2022-04-23 16:00:0023/04/22 | Futsal Settecamini — Real Mattei | 4 - 4 | G-Sportvillage |
| 2022-04-23 16:15:0023/04/22 | Atletico Pavona — Circolo Master 97 | 3 - 2 | Ok Club |
| 2022-04-23 18:00:0023/04/22 | Epiro C.a 5 — Sportingclub Santos Mmxix | 1 - 0 | Tobia Mario |
| 2022-04-23 18:30:0023/04/22 | Circolo Canottieri Lazio — U.S. Cures C.a 5 | 3 - 2 | San Gaetano C5 |
| 2022-05-07 15:00:0007/05/22 | U.S. Cures C.a 5 — Epiro C.a 5 | 2 - 2 | Palazzetto Palasabina |
| 2022-05-07 15:00:0007/05/22 | Sportingclub Santos Mmxix — Futsal Settecamini | 6 - 0 | Valle Aurelia |
| 2022-05-07 15:00:0007/05/22 | Real Mattei — Conauto Lidense C.a5 | 3 - 7 | Empire Roma |
| 2022-05-07 15:00:0007/05/22 | Ls10 — Atletico Pavona | 3 - 5 | Virtus Antica Aurelia |
| 2022-05-07 15:00:0007/05/22 | Bfsport — Futsal Tor Sapienza | 6 - 2 | Palasantarufina |
| 2022-05-07 15:30:0007/05/22 | Circolo Master 97 — Riposa | 15:30:0015:30 | - |
| 2022-05-07 18:30:0007/05/22 | Virtus Ostia C.5 — Circolo Canottieri Lazio | 2 - 5 | Lodovichetti A.C5 |
| 2022-05-14 15:00:0014/05/22 | Futsal Tor Sapienza — Real Mattei | 2 - 5 | Supreme Sport Village |
| 2022-05-14 15:00:0014/05/22 | Conauto Lidense C.a5 — Sportingclub Santos Mmxix | 4 - 2 | Lodovichetti A.C5 |
| 2022-05-14 15:30:0014/05/22 | Circolo Canottieri Lazio — Riposa | 15:30:0015:30 | - |
| 2022-05-14 15:30:0014/05/22 | Circolo Master 97 — Ls10 | 3 - 4 | Master |
| 2022-05-14 16:00:0014/05/22 | Futsal Settecamini — U.S. Cures C.a 5 | 4 - 10 | G-Sportvillage |
| 2022-05-14 16:15:0014/05/22 | Atletico Pavona — Bfsport | 5 - 0 | Ok Club |
| 2022-05-14 18:00:0014/05/22 | Epiro C.a 5 — Virtus Ostia C.5 | 2 - 1 | Tobia Mario |
| 2022-05-21 15:00:0021/05/22 | U.S. Cures C.a 5 — Conauto Lidense C.a5 | 7 - 3 | Palazzetto Palasabina |
| 2022-05-21 15:00:0021/05/22 | Sportingclub Santos Mmxix — Futsal Tor Sapienza | 7 - 5 | Valle Aurelia |
| 2022-05-21 15:00:0021/05/22 | Real Mattei — Atletico Pavona | 2 - 2 | Empire Roma |
| 2022-05-21 15:00:0021/05/22 | Bfsport — Circolo Master 97 | 3 - 2 | Palasantarufina |
| 2022-05-21 15:30:0021/05/22 | LS10 — Riposa | 15:30:0015:30 | - |
| 2022-05-21 18:30:0021/05/22 | Virtus Ostia C.5 — Futsal Settecamini | 18:30:0018:30 | Lodovichetti A.C5 |
| 2022-05-21 18:30:0021/05/22 | Circolo Canottieri Lazio — Epiro C.a 5 | 2 - 4 | San Gaetano C5 |
U.S. Cures C.a 5
Epiro Calcio a 5
Atletico Pavona
Bfsport
Virtus Ostia C.5
Circolo Canottieri Lazio
Real Mattei
Futsal Tor Sapienza
Sportingclub Santos Mmxix
Circolo Master 97
LS10
Futsal Settecamini
Bracelli Club
Futsal Ronciglione
Santa Severa Futsal
Ulivi Village Calcio
Virtus Anguillara Futsal
Virtus Monterosi
riposa
