| 2021-04-11 11:00:0011/04/21 |   Aranova — Citta di Cerveteri | 2 - 1 | Le Muracciole |
| 2021-04-11 11:00:0011/04/21 |   Vigor Perconti — Pomezia Calcio 1957 | 1 - 1 | Vigor C.S. |
| 2021-04-11 11:00:0011/04/21 |   Ottavia — Pol. Faul Cimini | 2 - 1 | Di Marco Ivo |
| 2021-04-11 11:00:0011/04/21 |   Fiumicino 1926 — Real Monterotondo Scalo | 1 - 3 | Desideri Pietro |
| 2021-04-11 16:00:0011/04/21 |   Civitavecchia Calcio 1920 — Boreale Donorione | 1 - 1 | Tamagnini Vittorio |
| 2021-04-18 11:00:0018/04/21 |  Pomezia Calcio 1957 — Academy Ladispoli | 0 - 0 | Comunale |
| 2021-04-18 11:00:0018/04/21 | Citta di Cerveteri — Fiumicino 1926 | 4 - 3 | Galli Enrico |
| 2021-04-18 11:00:0018/04/21 | Pol. Faul Cimini — Civitavecchia Calcio 1920 | 4 - 0 | Comunale |
| 2021-04-18 11:00:0018/04/21 | Boreale Donorione — Vigor Perconti | 1 - 0 | Don Orione |
| 2021-04-18 11:00:0018/04/21 | Real Monterotondo Scalo — Ottavia | 9 - 1 | Pierangeli Ottavio |
| 2021-04-25 11:00:0025/04/21 | Vigor Perconti — Civitavecchia Calcio 1920 | 1 - 1 | Vigor C.S. |
| 2021-04-25 11:00:0025/04/21 | Real Monterotondo Scalo — Pol. Faul Cimini | 2 - 1 | Pierangeli Ottavio |
| 2021-04-25 11:00:0025/04/21 | Ottavia — Citta di Cerveteri | 0 - 3 | Di Marco Ivo |
| 2021-04-25 11:00:0025/04/21 | Aranova — Pomezia Calcio 1957 | 2 - 1 | Le Muracciole |
| 2021-04-25 11:00:0025/04/21 | Academy Ladispoli — Boreale Donorione | 2 - 1 | Sale Angelo |
| 2021-04-28 16:30:0028/04/21 | Pol. Faul Cimini — Vigor Perconti | 5 - 0 | Comunale |
| 2021-04-28 16:30:0028/04/21 | Civitavecchia Calcio 1920 — Academy Ladispoli | 1 - 0 | Tamagnini Vittorio |
| 2021-04-28 16:30:0028/04/21 | Citta di Cerveteri — Real Monterotondo Scalo | 1 - 4 | Galli Enrico |
| 2021-04-28 16:30:0028/04/21 | Pomezia Calcio 1957 — Fiumicino 1926 | 1 - 3 | Comunale |
| 2021-04-28 16:30:0028/04/21 | Boreale Donorione — Aranova | 2 - 1 | Don Orione |
| 2021-05-02 11:00:0002/05/21 | Ottavia — Pomezia Calcio 1957 | 2 - 0 | Di Marco Ivo |
| 2021-05-02 11:00:0002/05/21 | Fiumicino 1926 — Boreale Donorione | 2 - 2 | Desideri Pietro |
| 2021-05-02 11:00:0002/05/21 | Citta di Cerveteri — Pol. Faul Cimini | 0 - 0 | Galli Enrico |
| 2021-05-02 11:00:0002/05/21 | Aranova — Civitavecchia Calcio 1920 | 3 - 0 | Le Muracciole |
| 2021-05-02 11:00:0002/05/21 | Academy Ladispoli — Vigor Perconti | 1 - 0 | Sale Angelo |
| 2021-05-09 11:00:0009/05/21 | Pomezia Calcio 1957 — Real Monterotondo Scalo | 11:00:0011:00 | Comunale |
| 2021-05-09 11:00:0009/05/21 | Boreale Donorione — Ottavia | 11:00:0011:00 | Don Orione |
| 2021-05-09 11:00:0009/05/21 | Pol. Faul Cimini — Academy Ladispoli | 11:00:0011:00 | Comunale |
| 2021-05-09 11:00:0009/05/21 | Vigor Perconti — Aranova | 11:00:0011:00 | Vigor C.S. |
| 2021-05-09 16:30:0009/05/21 | Civitavecchia Calcio 1920 — Fiumicino 1926 | 16:30:0016:30 | Tamagnini Vittorio |
| 2021-05-12 16:30:0012/05/21 | Real Monterotondo Scalo — Boreale Donorione | 16:30:0016:30 | Pierangeli Ottavio |
| 2021-05-12 16:30:0012/05/21 | Ottavia — Civitavecchia Calcio 1920 | 16:30:0016:30 | Di Marco Ivo |
| 2021-05-12 16:30:0012/05/21 | Fiumicino 1926 — Vigor Perconti | 16:30:0016:30 | Desideri Pietro |
| 2021-05-12 16:30:0012/05/21 | Citta di Cerveteri — Pomezia Calcio 1957 | 16:30:0016:30 | Galli Enrico |
| 2021-05-12 16:30:0012/05/21 | Aranova — Academy Ladispoli | 16:30:0016:30 | Le Muracciole |
| 2021-05-16 11:00:0016/05/21 | Boreale Donorione — Citta di Cerveteri | 11:00:0011:00 | Don Orione |
| 2021-05-16 11:00:0016/05/21 | Vigor Perconti — Ottavia | 11:00:0011:00 | Vigor C.S. |
| 2021-05-16 11:00:0016/05/21 | Pol. Faul Cimini — Aranova | 11:00:0011:00 | Comunale |
| 2021-05-16 11:00:0016/05/21 | Academy Ladispoli — Fiumicino 1926 | 11:00:0011:00 | Sale Angelo |
| 2021-05-16 16:30:0016/05/21 | Civitavecchia Calcio 1920 — Real Monterotondo Scalo | 16:30:0016:30 | Tamagnini Vittorio |
| 2021-05-23 11:00:0023/05/21 | Real Monterotondo Scalo — Vigor Perconti | 11:00:0011:00 | Pierangeli Ottavio |
| 2021-05-23 11:00:0023/05/21 | Pomezia Calcio 1957 — Pol. Faul Cimini | 11:00:0011:00 | Comunale |
| 2021-05-23 11:00:0023/05/21 | Ottavia — Academy Ladispoli | 11:00:0011:00 | Di Marco Ivo |
| 2021-05-23 11:00:0023/05/21 | Fiumicino 1926 — Aranova | 11:00:0011:00 | Desideri Pietro |
| 2021-05-23 11:00:0023/05/21 | Citta di Cerveteri — Civitavecchia Calcio 1920 | 11:00:0011:00 | Galli Enrico |
| 2021-05-30 11:00:0030/05/21 | Aranova — Ottavia | 11:00:0011:00 | Le Muracciole |
| 2021-05-30 11:00:0030/05/21 | Academy Ladispoli — Real Monterotondo Scalo | 11:00:0011:00 | Sale Angelo |
| 2021-05-30 11:00:0030/05/21 | Vigor Perconti — Citta di Cerveteri | 11:00:0011:00 | Vigor C.S. |
| 2021-05-30 11:00:0030/05/21 | Boreale Donorione — Pomezia Calcio 1957 | 11:00:0011:00 | Don Orione |
| 2021-05-30 11:00:0030/05/21 | Fiumicino 1926 — Pol. Faul Cimini | 11:00:0011:00 | Desideri Pietro |
| 2021-06-02 11:00:0002/06/21 | Real Monterotondo Scalo — Aranova | 11:00:0011:00 | Pierangeli Ottavio |
| 2021-06-02 11:00:0002/06/21 | Pomezia Calcio 1957 — Civitavecchia Calcio 1920 | 11:00:0011:00 | Comunale |
| 2021-06-02 11:00:0002/06/21 | Pol. Faul Cimini — Boreale Donorione | 11:00:0011:00 | Comunale |
| 2021-06-02 11:00:0002/06/21 | Ottavia — Fiumicino 1926 | 11:00:0011:00 | Di Marco Ivo |
| 2021-06-02 11:00:0002/06/21 | Citta di Cerveteri — Academy Ladispoli | 11:00:0011:00 | Galli Enrico |
Real Monterotondo
Aranova
Boreale Donorione
Pol. Faul Cimini
Academy Ladispoli
Citta di Cerveteri
Ottavia
Civitavecchia 1920
Fiumicino 1926
Pomezia Calcio 1957
Vigor Perconti
